This exercise aims to develop an IVIVC-PBPK model (part I) and mitigate a potential risk of BE failing by using virtual bioequivalence (Part II).
The second-generation antipsychotic (SGA) or atypical antipsychotic rebalances dopamine and serotonin to improve thinking, mood, and behavior. As a BCS class II compound, it is highly permeable, and bioavailability is limited solely by its solubility.
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