Workshop Day 2 (PAGE 2025)

Building Scalable PBPK-QSP Models: Modularization in MoBi for OSP Suite V12 

Join us for our second Satellite Workshop of the week!

Summary: 
The latest OSP Suite V12 introduces a revolutionary modularization approach that significantly enhances the flexibility, scalability, and efficiency of quantitative systems pharmacology (QSP) modeling and integrations with physiologically-based PK (PBPK-QSP). This full-day hands-on workshop will equip participants with the skills to leverage modular workflows in MoBi to build, extend, and refine PBPK-QSP models like never before. 

Led by ESQlabs scientists, attendees will start with a simple two-compartment model to grasp the fundamentals of modularization before diving into a real-world case study: modeling an ADC modality for tumor treatment. Participants will: 

By the end of the workshop, attendees will master the new modular approach in MoBi, learning how to efficiently build and manage complex models in a structured way. While automated model qualification will be touched upon as an outlook, the focus will be on hands-on modeling and modularization techniques that enhance collaboration, transparency, and reusability in PBPK-QSP modeling. 

Agenda Highlights: 

• Understanding modularization in OSP Suite V12 
  
• Adding new organs to PBPK models seamlessly 
  
• Developing effect models as independent modules 
  
• Modeling tumor treatment and large molecules with modular PBPK-QSP workflows 

Who Should Attend? 

This workshop is ideal for PBPK/QSP modelers, clinical pharmacologists, and researchers looking to enhance their mechanistic modeling workflows using the latest innovations in MoBi and OSP Suite V12. Whether you're new to OSP Suite or an experienced user, you'll leave with practical skills to create modular, scalable, and reusable models for drug development and translational research.  

Instructors: Dr Stephan Schaller, Dr Wilbert de Witte and Pavel Balazki 

The workshop fee includes catering and access to our training materials.