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Maternal-Fetal PBPK

Maternal-Fetal PBPK

MoBi/OSP-Suite Version 10

In this course, you will learn how to create a PBPK model of Metronidazole, an antibiotic against anaerobic bacteria. You will create
• a non-pregnant individual
• a non-pregnant population
• a pregnant population, and
• a PBPK model of Metronidazole.
The exercises are based on the published PBPK model of Metronidazole:
• Dallmann et al. 2018, Clin Pharmacokinet. 57(6): 749-768.

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