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Lysosomal Trapping (Team)
Lysosomal Trapping (Team)
MoBi/OSP-Suite Version 11
In this exercise, you will learn how to extend a PBPK model by new compartments and model the distribution of compounds based on partition coefficients. You will implement a simplified model of lysosomal trapping. Lysosomes are organelles within cells with low pH (4-5) that can bind basic lipophilic molecules.
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