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Lysosomal Trapping

Lysosomal Trapping

MoBi/OSP-Suite Version 9

In this exercise, you will learn how to extend a PBPK model by new compartments and model the distribution of compounds based on partition coefficients. You will implement a simplified model of lysosomal trapping. Lysosomes are organelles within cells with low pH (4-5) that can bind basic lipophilic molecules.

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