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Drug-Drug-Interactions (DDI)

Drug-Drug-Interactions (DDI)

PK-Sim/OSP-Suite Version 9

In this course, you will learn how to create simulations based on the compounds database of PK-Sim. You will simulate the PK of itraconazole and its metabolite hydroxy-itraconazole, both being substrates and inhibitors of the enzyme CYP3A4. Moreover, you will model the effect of itraconazole administration on the PK of midazolam.

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