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Workshop (PAGE 2022)

OSP-Suite/esqLABS GmbH

Length: 1 Day

June 28, 2022
8:30 am - 5:30 pm
On-Site Academia
0,00 €
On-Site Industry
0,00 €
Online
0,00 €
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Content

esqLABS is conducting a FREE workshop on Tuesday, June 28th, demonstrating the application of PK-Sim® and MoBi® (OSP-Suite, www.open-systems-pharmacology.org) for use in physiologically-based pharmacokinetic (PBPK) and quantitative systems pharmacology (QSP) modelling and simulation applications as an in-person & virtual satellite event to the PAGE Meeting 2022 in Ljubljana, Slovenia.
Participants will learn how to:

  1. Access and use OSP community qualified content and integrate qualified compound model templates within projects (including a preview of a new workflow with the to be released Version 11 of the OSP Suite (or beta-release))
  2. Evaluate Drug-Drug-Interactions (DDIs) using PK-Sim and the qualified DDI networks and corresponding model libraries on GitHub and how qualified intended use scenarios are reported.
  3. Customize & extend PBPK models to simulate disease mechanisms and drug effects (PBPK/PD or PBPK-QSP models). This is exemplified on a protein/antibody PBPK model for antibody-drug-conjugates (ADCs) for the treatment of tumor growth considering target-mediated drug disposition (TMDD)

The workshop will not require prior experience with the software but will still be of relevance for advanced users.

Hands-On Material

The workshop will be conducted using our newly launched online academic learning & industry training platform for the OSP-Suite with up-to-date and curated application examples for PK-Sim and MoBi in PBPK and QSP.

Participant access to our learning & training platform for the workshop material is optional and not required to follow the workshop. However, the material is highly recommended for continuous and in-depth training on the software.

For academia, access to the workshop material is free:
esqLABS' Academic Learning Center

For Industry, access to the workshop material needs to be purchased to cover our costs of continuous maintenance of the up-to-date and curated training material and to enable free access to the material for young researchers in academia. Add to Cart:

A free OSPS update to Version 11 will occur before the event.

    Preparation

    • You will need your laptop, with the following software pre-installed.
    • To download the software version 11, please click here
    • Download & install the R distribution (Ver 4.0+) from here
    • Download & install FREE RStudio Desktop (a GUI for R with additional functionalities for e.g. debugging and code visualization) from here

    Location

    The location for the face-to-face workshop is the PAGE Meeting venue (Hall E3, two levels below the main meeting).

    Online participants will receive dial-in information 1-2 weeks ahead of the meeting.

    People

    The workshop will be held by consultants and scientists of esqLABS GmbH with extensive experience in the use of PK-Sim® & MoBi® in all application areas.

     
    Dr. Stephan Schaller (CEO and Lead Scientist)

     
    Pavel Balazki (Senior Consultant/Lead ToolChain Development)